IGF-1 LR3 1 mg

Long R3 IGF-1 is a synthetic analog of human insulin-like growth factor-1 (IGF-1), containing a glutamate-to-arginine substitution at position 3 and a 13-amino-acid N-terminal extension. These modifications prevent binding to IGF-binding proteins (IGFBPs), resulting in a significantly prolonged half-life and dramatically increased biological potency in cellular growth and muscle hypertrophy studies.

Product Specifications

Key Research Applications

• Researching IGF-1 receptor (IGF-1R) activation and intracellular Akt/mTOR signaling.
• Studying cellular hyperplasia, muscle cell proliferation, and protein synthesis.
• Exploring nutrient transport, glucose uptake, and metabolic partitioning in skeletal muscle.
• Investigating cell survival, cellular differentiation, and tissue hypertrophy in cell culture models.

Reconstitution & Reagent Handling

Reconstitute with sterile bacteriostatic water or 0.6% acetic acid. Swirl gently.

Storage & Stability

Store lyophilized powder at ≤8°C. Reconstituted solution should be stored at 2°C to 8°C.