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FOXO4-Dri 10 mg (Proxofim)

Original price was: $299.90.Current price is: $269.90.Save $30.00

1000 in stock

Quantity Unit Price
2 - 4 $256.41
4 - 9 $242.91
10 - 19 $229.42
20 + $215.92

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Product is provided as a lyophilized powder in a sterile glass vial. All researchers are assumed to acquire all necessary supplies to conduct their research, such as reconstitution solution and alcohol pads to maintain sterility.

Ships same-day if ordered before 12 PM EST. Estimated delivery: 2 – 5 days

ev-1780957555865-86

Description

FOXO4-Dri 10 mg (Proxofim)

FOXO4-Dri (Proxofim) is a retro-inverso D-amino acid peptide designed to block the interaction between the transcription factor FOXO4 and p53. By preventing FOXO4 from binding to p53, the peptide allows p53 to localize to the mitochondria and trigger apoptosis specifically in senescent cells. It is widely investigated as a senolytic agent in longevity and tissue rejuvenation research.

Product Specifications

Chemical Formula C228H388N86O64
Molecular Weight 5358.05 g/mol
CAS Number 2460055-10-9
PubChem CID 167312269
Purity >99% (Guaranteed)
Physical State Lyophilized Powder (Sterile Vial)

Key Research Applications

  • Researching senolytic mechanisms and selective apoptosis of senescent cells.
  • Studying FOXO4-p53 protein-protein interaction and mitochondrial localization.
  • Exploring healthspan extension, tissue rejuvenation, and organ recovery in aging animal models.
  • Investigating chemotherapy resistance and cellular senescence pathway regulation.

Reconstitution & Reagent Handling

Reconstitute with sterile bacteriostatic water. Swirl gently; do not shake.

Storage & Stability

Store lyophilized powder at ≤8°C. Store reconstituted peptide at 2°C to 8°C.

RESEARCH USE ONLY: This product is a high-purity laboratory chemical. It is synthesized and supplied strictly for laboratory research, in vitro studies, and experimental use. This product is not approved for human or veterinary use, diagnostic procedures, or therapeutic administration.

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